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Abstract A novel core-shell DNA self-assembly catalyzed by thiol-disulfide exchange reactions was proposed, which could realize GSH-initiated hybridization chain reaction (HCR) for signal amplification and molecules gathering
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A previous study supported this, showing that treatment of SLC1A5 -knockdown HNSCC cell lines with V-9302 led to marked inhibition of glutamine metabolism, thereby suppressing growth and proliferation both in vitro and in vivo 97
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