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It should be noted that nitrofurantoin followed a slower kinetic profile, characterized by RecA foci appearing at 10 min, followed by nucleoid relaxation, loss of DAPI signal, and loss of RecA foci at 30 min, while Cu 3 -TC-Pyr already showed DNA dispersal at 10 min (Supplementary Fig
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Such carmustine wafer allows for delivery of the drug directly to the site of the brain tumor, the amount of carmustine received depends on the size of the cavity and how many wafers can be put into place 7,8,9,10,11
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