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Our ChIP-qPCR validation analysis on five of those genes, Ajuba , Lgals3 , Synpo , Slc35f6, and Gstm2 , shows NaBt-mediated enrichment of H3K27ac mapping in their promoters in accordance with the ChIP-seq results (Fig
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It could also be a symptom of Adrenal Fatigue (AF), which is caused by chronic stress and results in the overuse of the NeuroEndoMetabolic (NEM) stress response, keeping cortisol levels high
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