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Two GSK-3 isoforms exist, GSK-3α and GSK-3β, both of which are inhibited by growth factors via Akt phosphorylation of their N-terminal Ser-21 and Ser-9 residues, respectively
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A portion of lysate was suspended in 0.1% N-lauroylsarcosine and used for analysis of protein content by Bradford assay (64)
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